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Michael E Charness Selected Research

Fetal Alcohol Spectrum Disorders

1/2020Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood.
1/2019Clinical presentation, diagnosis, and management of fetal alcohol spectrum disorder.
1/2018L1 coupling to ankyrin and the spectrin-actin cytoskeleton modulates ethanol inhibition of L1 adhesion and ethanol teratogenesis.
11/2014Effect of lipid raft disruption on ethanol inhibition of l1 adhesion.
4/2013Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule.
11/2012Ethanol disrupts axon outgrowth stimulated by netrin-1, GDNF, and L1 by blocking their convergent activation of Src family kinase signaling.
5/2011Two alcohol binding residues interact across a domain interface of the L1 neural cell adhesion molecule and regulate cell adhesion.
1/2011Effects of ethanol and NAP on cerebellar expression of the neural cell adhesion molecule L1.
1/2008An alcohol binding site on the neural cell adhesion molecule L1.
10/2006Maternal oral intake mouse model for fetal alcohol spectrum disorders: ocular defects as a measure of effect.
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Michael E Charness Research Topics

Disease

12Fetal Alcohol Spectrum Disorders
01/2020 - 07/2003
8Teratogenesis
01/2020 - 10/2002
2COVID-19
01/2022 - 01/2021
2Microphthalmos
12/2007 - 10/2006
1Overweight
01/2020
1Type 2 Diabetes Mellitus (MODY)
01/2020
1Obesity
01/2020
1Genetic Predisposition to Disease (Genetic Predisposition)
04/2013
1Binge Drinking
01/2011
1Coloboma (Colobomas)
10/2006
1Anencephaly (Aprosencephaly)
01/2005
1Neural Tube Defects (Exencephaly)
01/2005
1Dystonia (Limb Dystonia)
08/2003
1Dystonic Disorders (Writer's Cramp)
08/2003
1Muscular Diseases (Myopathy)
08/2003

Drug/Important Bio-Agent (IBA)

13Ethanol (Ethyl Alcohol)IBA
01/2020 - 10/2002
4Peptides (Polypeptides)IBA
01/2011 - 10/2002
3Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
11/2014 - 01/2008
2Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)IBA
01/2018 - 05/2011
1AerosolsIBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2022
12019-nCoV Vaccine mRNA-1273IBA
01/2021
1VaccinesIBA
01/2021
1Triglycerides (Triacylglycerol)IBA
01/2020
1Biomarkers (Surrogate Marker)IBA
01/2019
1SpectrinIBA
01/2018
1AnkyrinsIBA
01/2018
1MAP Kinase Kinase 1IBA
04/2013
1Netrin-1IBA
11/2012
1Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA
11/2012
1Proteins (Proteins, Gene)FDA Link
01/2011
1Peptide Hydrolases (Proteases)FDA Link
06/2004
1Mitochondrial DNA (mtDNA)IBA
08/2003
1DNA Restriction Enzymes (Restriction Endonuclease)IBA
08/2003
1NucleotidesIBA
08/2003
11-Octanol (1 Octanol)IBA
11/2002
1NeurotoxinsIBA
10/2002
1AlcoholsIBA
10/2002

Therapy/Procedure

1Long-Term Care
01/2022
1Therapeutics
01/2019
1Cognitive Training
01/2019
1Intraperitoneal Injections
10/2006